Adding to Torfinn's post. A few words of caution, if you open any existing files in the 2018 trial, make sure you immediately use 'Save-As' and save under a new name, (or copy the existing file in windows explorer before opening in 2018).
It has happened in the past, where people have tested a new version and accidentally saved an existing file, thus preventing it from opening again in previous TC versions.
I would expect your system to cope, though I've never owned a Quadro card. But note, 2018 does not include RedSDK (its a plug-in now). so materials / rendering in Lightworks will be a bit different to what you are used to. some people prefer Lightworks).