Sorry I don't have designer so can't verify what's written below, as I can only comment on what I found in Pro.
Basically you have quite a few problems with the file, possibly 3 or 4 problem layers are F2 anno, F3 anno DIM, F3 doors/windows, and int-kitchen.
Personally I think it is recoverable but would take a few hours to isolate all the faults, I tried copying into new file but the faults copied also, if you have a backup copy that doesn't exhibit the problems then you would be better using that, or you could copy each layer one at a time into a new file (saving as new name after each copy) to isolate the problems.
I'll have a go for a while and report back unless someone has sorted the problem in the mean time. - OH by the way, John was partly right, for starters if you open A COPY of your file and drag a selection window Left to right over your drawing, then hold down the shift key and drag right to left, the drawing will de-select but still show like something is selected way out in space, looks like too far for TC to even display, just hitting delete key sorts this bit out, but as I say you have other problems.